MAIN SUBSTANCE : Isotretinoin

CATEGORY : Oral steroid


DOSAGE : 10-40mg per day

PACKAGE :  10mg/tab × 100 tablets

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Pharmacom Isotretinoin, also known as 13-cis retinoic acid is an oral pharmaceutical drug primarily used to treat acne. Rarely, it is also used to prevent certain skin cancers, the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis.

It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body.

Pharmacom Isotretinoin amplifies production of neutrophil gelatinase-associated lipocalin (NGAL) in the skin, which has been shown to reduce sebum production by inducing apoptosis in sebaceous gland cells, while exhibiting an antimicrobial effect on Propionibacterium acnes. The drug decreases the size and sebum output of the sebaceous glands. Isotretinoin is the only available acne drug that affects all four major pathogenic processes in acne, which distinguishes it from alternative treatments (such as antibiotics) and accounts for its efficacy in severe, nodulocystic cases.

Oral Pharmacom Isotretinoin is best absorbed when taken with a high-fat meal, because it has a high level of lipophilicity. The efficacy of isotretinoin doubles when taken after a high-fat meal compared to when taken without food. Due to Isotretinoin’s molecular relationship to Vitamin A, it should not be taken with Vitamin A supplements due to the danger of toxicity through cumulative overdosing.

The results are evident, with systematic use. The preparation is able to enhance regeneration processes in skin. The mechanism of action is based on the ability to influence the composition of skin sebum, reduce its production and ensure rapid removal from sebaceous glands. Roas, has an anti-inflammatory effect that aims to eliminate inflammation around glands at acne. Roas, exhibits a pronounced keratolytic effect which involves normalizing cell renewal and prevents clogging of sebaceous glands. When taken, the production of sebaceous glands is suppressed, the ducts are narrowed and their quantity is reduced. The drug is used even when other agents have failed to solve the problem. With its help, treat acne diseases that have not been eliminated by other drugs, narrow-cystic, conglobate and pries that can leave scars. Throughout treatment, it is necessary to monitor liver care, sugar and lipid levels. In order to reduce the toxic effect, it is necessary to use the preparation in combination with vitamin A.

The preparation must be taken in these doses, otherwise side reactions in the form of rash, dermatitis, sweating, deterioration of vision at night, headache and other symptoms may occur. “Roas” Pharmacom: Reviews about Roas, very good. All athletes who faced the acne problem, after the use of the drug, felt a significant result. The substance refers to fat-soluble, so it has the property to accumulate in the fat depot and gradually release into the blood. This provides a long-term action. It is necessary to adhere to all rules of intake and dosages, then the effect, is completely positive. Everyone who used the agent got rid of pimples completely or almost completely. Where to buy “Roas” Purchase Roas, can be found in the online store. The tool must be original to ensure the highest possible result. To protect against forgery, a security system is developed in the form of coding of each unit of product. The code is listed on the package, it can be checked on the website of the company that produces the drug. Contraindicated in pregnancy and less than two months before conception (teratogenic and embryotoxic action).

Isotretinoin is the most effective drug for treating acne on the market. The most common adverse effects are a transient worsening of acne (lasting 2–3 weeks), dry lips, dry and fragile skin, and an increased susceptibility to sunburn. Uncommon and rare side effects include: muscle aches and pains, and headaches.



10-40mg per day.







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